Mantis

Active

Digital Twins of humans

Winter 2026Founded 20253 peopleNew York City, NY, USA

mantisbiotech.com/ ↗LinkedIn ↗X ↗Crunchbase ↗

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AI insightcan contain mistakes

Human Behavior Digital TwinAPI/InfraEnterprise research and simulation teamsLow competition

Moat

LLM + physics simulation combo for human behavior is novel; rare behavioral data creates defensibility.

Key risk

Ethical concerns around human digital twins may limit adoption; technical accuracy is uncertain.

Why now

LLM capabilities and compute availability enable realistic human behavior simulation.

Competitors

Emerging space, academic simulation

↻ Pivot / rename signal

This company has previously operated under “Mantis Biotechnology”. A rename frequently marks a pivot in positioning or product — useful raw material for variant ideas.

About

Mantis is a digital twin company that combines LLMs with high-fidelity physics simulations in order to convert rare and difficult-to-access human behavior data into predictive models.

Founders · 1

Georgia WitchelFounder

I'm an Ex-elite ice climber turned repeat computer science / biomedical founder. After bringing climbing to an Olympic stage (Lilihammer 2016), breaking 8 world records, and developing the sport of ice climbing, I dropped out of high school, got a degree in CS from Harvey Mudd, was a founding engineer for a sports tech company, founded a YC company (Louiza Labs), and earned a master's in Bioengineering.

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B2B Infrastructure

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