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Natural hydrogel to keep internal organs scar-free after surgery
TYBR is developing a hydrogel to limit internal scarring after surgery. The naturally derived material is applied to coat tendons at the end of surgery to improve healing outcomes for the millions Americans who undergo tendon or ligament surgery each year.
TYBR Health offers The B3 GEL System, a flowable ECM-based hydrogel designed to protect healing tendons and ligaments to reduce scar formation and preserve mobility after surgery. It is positioned as an intraoperative gel that conforms to tissue, maintaining tissue separation during healing and integrating into surgical workflows.
The B3 GEL System delivers a flowable, tissue-conforming ECM-based gel that provides a protective environment around healing tendons and ligaments. It is color-coded (blue) for precise application, maintains biomechanical separation of tissues during the healing window, and is designed to prevent restrictive scar formation while supporting natural healing. Validation studies indicate the gel preserves normal tendon gliding mechanics even when over-applied, with no mechanical impingement or drag within the sheath.
Who it’s for: Surgeons and surgical practices specializing in tendon and soft tissue repairs seeking to reduce post-operative scarring and improve mobility outcomes.
Funding/hiring not stated; evidence-based research collaborations and clinical validation mentioned
Tim Keane is a co-founder & CEO of TYBR Health. He has expertise in regenerative medicine and biomaterials and over 30 publications to support the science behind TYBR's technology. Prior to co-founding TYBR, Tim completed a Biodesign Fellowship at Texas Medical Center. He has a PhD in bioengineering from the University of Pittsburgh and completed post-doctoral fellowships at Imperial College London.
Alex is a cofounder and TYBR’s CTO. He has a BS and MEng in Biomedical Engineering from Texas A&M University and a PhD in Mechanical Engineering from University of Houston. He has nearly a decade of experience in medical device development for dialysis access, vaginal dilators, and ventricular assist pump design. At TYBR, he prototypes the delivery system for ECM spray, plans studies, and manages manufacturability & cost control of the delivery device.
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