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Promakhos Therapeutics

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A therapeutics platform for curing inflammatory disorders

Summer 2021Founded 20212 peopleBoston, MA, USA
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This company has previously operated under Promakhos Therapeutics Inc.. A rename frequently marks a pivot in positioning or product — useful raw material for variant ideas.

About

We are building a platform of bacterial molecules to awaken our body’s innate ability to control inflammation and heal. Our first indication is Crohn’s Disease, which affects over 500,000 Americans at an annual cost of $10B. After Crohn's disease, we are going for type 1 Diabetes and Multiple Sclerosis.

Founders · 2

Katerina Chatzi
Katerina ChatziFounder
Harvard

I believe we can discover unexpected things that can transform our lives. I have lived and performed research in 4 countries and 2 continents. Previously I was a postdoc at Harvard. I founded Promakhos because I think we have given to “autoimmune” diseases a grossly misleading name and we treat them in a primitive way. Promakhos means the first to enter a battle. In ancient Greece Promakhos was the strongest to put in the front line of an army so that they will not even have to start a battle.

Jasper Edgar Neggers
Jasper Edgar NeggersFounder
MITHarvard

CSO and co-founder of Promakhos. In high school, Jasper built a web-shop. He obtained a BSc, MSc and PhD in Biomedical Sciences from KU Leuven. He pioneered the use of XPO1 inhibitors for treating cancer and invented a CRISPR-directed evolution technology for drug target deconvolution. Jasper then joined the Dana-Farber Cancer Institute & Broad Institute of MIT and Harvard to identify and validate new drug targets for gastrointestinal cancers. Now, he develops drugs for chronic inflammation.

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